DENATONIUM AS A BITTER TASTE RECEPTOR AGONIST MODIFIES TRANSCRIPTOMIC PROFILE AND FUNCTIONS OF ACUTE MYELOID LEUKEMIA CELLS

Denatonium as a Bitter Taste Receptor Agonist Modifies Transcriptomic Profile and Functions of Acute Myeloid Leukemia Cells

The contribution of cell-extrinsic factors in Acute Myeloid Leukemia (AML) generation and persistence has gained interest.Bitter taste receptors (TAS2Rs) are G protein-coupled receptors known for their primary role as a central warning signal to induce aversion toward noxious or harmful substances.Nevertheless, the increasing amount of evidence abo

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Evaluation of the endovideosurgical treatment efficacy of patients with various forms of infertility in a gynecological hospital

Infertility is a condition of the reproductive system, which is expressed in the absence of clinical pregnancy after 12 months of regular sexual activity without contraception.Despite the achievements of reproductive medicine, the problem of infertile marriage is far from being resolved.Restoring fertility in married couples requires rapid developm

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